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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e1a2e006b68a39e0608ce63e9f1f2507f1cf4ab232b70ff67ac16a25f4bf19' 
  AND token = 'BHQ3Iq0oZIENAnuJenBGz5Ez37ecYHig4Dqiq+xV+6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}