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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6df21c5071976c4ceff7c7071ede766f77b9d296e9f86a13f1fc79d7f73fc36' 
  AND token = 'ffWpziF8/E3/s3hDVRLQ+w4TTKdG98NKqAvmbltw1EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}