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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7544417057e59cd5e1435a00ec2e2fceaeefcd972a3a768d136ec166afeb6998' 
  AND token = 'oyzaswAtyuhb3rKRFVqsq4sDXwbmSRcx/45niZUzmMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}