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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10bd249f131e41a46a87848a9f903f2ce50ac0df8e5b57d72473a53d02ce27c7' 
  AND token = 'zEWLUUX+MLgq4dgwk/HYrMDMIYMQn9skYY8+1W/SKXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}