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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c922a51adf19aa2569a6487f41c52c525eaa6ac25b99037c1e9f5a1a0bbd10' 
  AND token = 'c86uSmlaA6Uss6zY7UvuQmLCblpTY5R+rztO5jLrPMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}