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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6042c9de971596869dbbd79e506b7a0fdd0b21d17718d22cb9e02b4dfe7fd3f5' 
  AND token = '/Mo/pasGdU3XOtyBzFQWYw95wwGfdIWJiXQyr5AKipM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}