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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29527ca5b38465ac9fd7f761a77312efdfcac77bb7dbb91797775a39badf3e1a' 
  AND token = 'COHj6Zr3R6cImXhgenxHM7MIKvK4u96X63fSgaBStBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}