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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '536decba8f9329d6981d18840fa95c57a5d19e0fa21f0aae5272e920daac860f' 
  AND token = '5LGApYIOibnxskPHz8oR30YCzFKS1E1DsboC2036kpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}