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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1534b43a9bf3af09a5f48d4f9444e3de1e9d44fd2c451df7e2c0b1b7652535' 
  AND token = 'DYfvWW9AMq9YvQEtp2rYf4GTCuzz/lI2YIqIlZ1+du4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}