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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce33584549d1f7964a70f55174fdf0c34dd3e12e3b12b39956ab772f10bd9682' 
  AND token = 'I2XZoW9/uKLFAh0Obw8EV7bpCMpspIFs65CWpLNHxaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}