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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf29ba216299269aaf2a55f777fc4690d0e88d781395a9bd10f41e66c062314' 
  AND token = 'V2/esXKzScoA2AvAn3M0phu117aKA/iOmx/pBLFgtIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}