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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4f1988de7d03b4af8aca25b669436f3c6930628e94239832c9c0536567de90' 
  AND token = 'f73wz8m6f0FPUO7dqR8Ucrkr6RezoteS3AJTQbElQBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}