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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81007aad94d6f5c13ccda6c97146ba8b0784c2270ea8daf63d4c5d4538028c6c' 
  AND token = 'TEb8uq+Bxrj3Q9NNO+3yiBP0bAEZOEoONvK/M58Qy90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}