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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7961d17d79d60227a7dc2b8d7636e3065244af9d042455fcc8ed0c17a4bee385' 
  AND token = 'axcXznSGHPD3MUrXkFOlBL8/hu5zZM6Be7OoW6aH3rg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}