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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b79dc6bdcd03b5d64e68749224208625a41d3dbcebfbd4baaab87fcd6bd7a52' 
  AND token = 'QUm6vpfUpu2kzJevIbQK+74UPX0/MEm9SM7XWxy9AiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}