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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a888cc58323e7e2b3e7b2f8c61fb92c927ab4c8e9c5ca3894e9766053f0dcad8' 
  AND token = 'RrHV7MVVg3a83L1WfRJEgdmbJ+YfFf86HVGLGwvBMSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}