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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd567d224522839c2518c90cf92f20dbcadb4dd18762a083019b1a354597173b' 
  AND token = '685HIlHG2sRgw0acPRSbKvd1reumb+aMc2kD8WmZ0W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}