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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4665e38e7ff36a799d000cb9305bd0e28cb1418aebc0b2b396764023db6d8b' 
  AND token = 'C8KYabQGzdCSTWCbPFEG3wMQYDddqDnjxOBJYIbdWz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}