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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5552584a97e71f7042e079c961d01cb1a1ba7d3df412e76cc7d44378e34d019' 
  AND token = 'Tqpe9mMFTKF6ilUuv3zTghGft1b+cp9SVKKL0kXm+wA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}