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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5d402af7691e33a8b3f72ffd7231b4fb0873800f014c0089dd331ae24763271' 
  AND token = 'DkpFDN4dxSrAIug9x0AVsXOJzHqIb/jzC1SvAAHpBxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}