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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82195a9b9b11d49fe9b09fd2a9cea097f1703087e21621ef56eea365aba5fbe9' 
  AND token = 'LgFfKgdH+AUmCMWZkDoD9vwI34nPMDCfGZyeoyS0l7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}