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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50da77e705f0e4d015bf552af9eb89220ed283db20cbe0c06ca2f60d8def45c5' 
  AND token = '0PQmfqIFB0rqoDh217MKk/Bxa869ibtsGtATpjOzG5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}