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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40d386e06267f9d635f5304a53f2ccb2fc260bb624eecb7cb19533ca8b6dc7b4' 
  AND token = 'F8nbqDmXfxVI1SfoBeI6Q5xWYxmhe+Tm/81qwUP/oN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}