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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756819e62c0b2e8f2492b5d43570e288a67b25000dc922729b74de5b0fd58b0e' 
  AND token = 'S5RuTp++vCU+XSZKs4TUWjQqIrZE5UF60N4RQnMPcB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}