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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ba52c43c65f9482eb597ddadbe41a754b1ec22acb2304ec2c83c3914b641867' 
  AND token = 'kW/p7/aHNL906vpEuLKVaQvGYgxt4GDSHuX20eBHMMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}