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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a28812d9381865645937a0879fceec0f795196a27dc4b792dfdf6ac4f20bd6' 
  AND token = '21/g0LCF+m/YEMTXyMpmrI7D/GtXU46+Tf99uZxnGRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}