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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e7d8a690814ec667c393d9ecd13f5b9f444ecc7087253b7614cfa043031142' 
  AND token = 'CAjreoYqsF/2eFmG3aueEgFtzxNiAQHq6mhit2B1YBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}