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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4cfff727280361730c25d871b33a967e998699706b7d84f84a194f434a53aea' 
  AND token = 'tm/6Qi0WbYxmIn9Mx1ZoG90UDkl6lDp+2KCAeQS6gHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}