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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57c7fb9a928b09e00a28a0c9f782a5b650c270d8eedaf67bdde575dd8213d9eb' 
  AND token = '0x+8S1wB0rx3YMpR1LcmlBYvqJSLxbOYtElfSNHJ2CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}