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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9074ab6f4a5cb6ce4344afa42517c5a630d56042696119bc8dd225bdb614ee97' 
  AND token = 'AEYoYQmFBLCTfNuLvhBe15eSQBAx5GAczRQWPdmX+L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}