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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1c7d659f25734e1f3ce8df23725871d004057075904501871b3825a0bf5d6af' 
  AND token = 'rxNF8bFUcEvNponls/A0vCV5IQziDDpq83JYrMuN1rI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}