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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5787c8b170940d47cb202cdb9a81425ad8be07b9e0414aeb175f65c6868dda0' 
  AND token = 'rYia9BXAS7/0I7vNqGB7kjU0MrxiCGnEQhxpONM/AYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}