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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b884951893cf448a94d84cbb6c7e9f8d8263b4ddc6d9d47590c3d959ca98099' 
  AND token = 'HFNuUuNiJjhT+9ZMJxN+NSPWodYTPd/Ms8lAVSivnT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}