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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '879646d61be117c88f69ec1c5e235c682b5eaed6f4024f5e95dcbe6079e0e72d' 
  AND token = 'fQtBn3k2/1sM5wwkDvn3yW+Yic1GnsJIBgKZ10Ewxis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}