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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6cdd3ac78c639624a4d029d6ee203a925f9272c9f61bd2a57cf150769abe58' 
  AND token = 'Ram8nMIBVFaNyC4NNnrIOv7/QSNYFNR+ZPIr1zUNNKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}