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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '462af0dc1f3427f04769a4e4067984f6f97bb518b160b0a8d849b77b08ec2148' 
  AND token = 'nS7lQx3nBNVm+t7RhqF9ZsD0Bl9Kvu9bL7Rsav5hWB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}