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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1402a28f86c9bd869d43399a6b3ad452580d9ceb93b14a169099e612b946b2' 
  AND token = 'gyEknpiCOIt1i3fL1EqZPfA9tJU5lk6EWj3qSBFvt6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}