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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d39ecff232c7a86f31be58f5c123a7eab0ab6b58c8a1edaa7063669c49ae22c' 
  AND token = 'QP26hG5QKbWQJBOz/zF3zUp4QAQOUt/kRjzenJeGxMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}