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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d17a0ed906fa25db512fcd2651ae26195fd52598a4541292a1ac5cabe962f1' 
  AND token = 'ZjDkolNqY5hNxSO6++ndhAt5WD2eoUBShmXvEnnU7kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}