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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35bb97fa7380bce9bb9cea21163511dd97234d8c6721c396fa6002188424080f' 
  AND token = 'gFJN2gFoZDs2TraH9qT04a22GfoHsm88b2pJ9SBH+J0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}