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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b69314abbd71d3f588acf537f679d3b16fad380655f8c3230d93758a7691b49' 
  AND token = 'YCZV09UAI0dTgmc7toziplICv3ZWRt79JjIxxK2lduc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}