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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9d2f718af351b91f28cc85f93818a8eb2577d48b1f0f6f478bd42c381cce8bf' 
  AND token = 'xBVQ0c0P/7CGHTTEHSBb3SD/2TmkxVM++7C1At+12eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}