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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '116dce1cf605865f20aa44591cf4eb9038c5b76c61a3ee271ed72c4c1063084d' 
  AND token = '00f7Uu791SfuG1BwzErEv4mq4oG6XRu2UkuoULm8kGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}