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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7e2b6b95b6ab1bd2c1d1a719b96505c3da64550914b69b1ce4c41973251919' 
  AND token = 'uUzxa0LHg6RBnQj4d4a+8tyElZwcUuw/fRFTlXUT4no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}