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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af1fce9007969ad75bf7357919fd190b233285f5c914cdce4f17fe02363de36b' 
  AND token = 'dKCFf+PvHFH+dF+e/4TQbuKpL8GCSEe3TkHUHT/h46c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}