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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd00f27403eb95e9bd8e32cfffb91ba0ba27e1573830b1518917b63bbe1bd18' 
  AND token = 'G2rRpY4QmLi/D16Tu7NtISRJd3D4u0KsGU260DOwI3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}