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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e921f4a1a95fb723b42ce1be9744c7c471e8265c3a966566803db5f3960b8ee2' 
  AND token = '1XygH4ym5e/YmT9dpAg+7E4WqW3pwINMXqUj8phrUY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}