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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b0642aeef5e55a3e895d0f5828a5663ff8b8591657bec1271cf2c3cff9c5d0' 
  AND token = 'aVbNzDdOtwOvt65HkzgM74Z+vZrlq5MHfp/HfR7oDnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}