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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbcd4226a393d30deb82f53c759f9009687a338d91d49946e9095ceb828b7199' 
  AND token = 'aU9HrlsZ43y+ru4TB0/LdKs09DGzGYx3pto8zAG/+70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}