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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6be1897523c3bc6fb30a19263c4b64cff12d4e96e2c09bec5292cbb82dd296' 
  AND token = 'D5zjzE7mTm+H6u5W8ty68DidblSjHCVQ4qqtav/7bPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}